
Perricone MD Deep Crease Serum is a product with 45 ingredients: Acyl-Glutathione, Water, Propanediol, Squalane, Hydrogenated Polyisobutene, S-Palmitoylglutathione, Dimethicone, Glycerin, Macadamia Ternifolia (Macadamia) Seed Oil, Xylitylglucoside and 35 more.
Contains: AHA - Lactic Acid; Antioxidant - Macadamia Ternifolia (Macadamia) Seed Oil, Tetrahexyldecyl Ascorbate, Dimethyl Mea, Tocopherol, Rosmarinus Officinalis (Rosemary) Leaf Extract;
Organic score: 36% natural, 53% chemical. Vegan - No; Cruelty free - No; Reef safe - Yes;
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Concerns
INCI - Full Breakdown
Water is a great solvent. It’s neutral and doesn’t provide any strong positive or negative effects. It just helps components to mix better and to transport active components.
Propanediol is a good solvent, emollient and humectant. It helps to moisturize the skin and prevent moisture loss. In haircare products, it conditions hair and improves absorption of the product.
Squalane is a more stable equivalent of Squalene. It is a very important component of our skin. It’s a major part of natural sebum that forms a protection barrier on the skin's surface. If the barrier isn’t strong enough, your skin will become more sensitive. Squalane helps to keep skin hydrated, protects it from the negative impact of the environment, lowers irritation, stimulates regeneration, and removes dryness. It is accepted by our skin very well and will not cause allergic reactions.
Dimethicone is the most popular silicone. It makes the skin softer and forms a film adding smooth and silky feeling. This film not only improves how the skin feels but also works as a protective barrier. It also improves the visual appearance of your skin by filling small wrinkles. That's why some people think dimethicone removes wrinkles. Actually, it does not. It's just a visual effect.
One of the most important characteristics of this component is that it helps to spread other ingredients evenly on the surface to provide good coverage. It's very important because you want all your skin cells to receive an equal proportion of the components.
Dimethicone is considered as safe, but remember that it is rather difficult to wash off! This may lead to clogged pores and acne if you use it too often and don't wash off quite well.

Glycerin is one of the most outstanding and helpful skincare components. It's used in many skincare products because it works and provides notable results. It's one of the best moisturizers. Molecules of Glycerin can absorb water and deliver it into deep layers of the skin making it hydrated.
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