
Perricone MD Intensive Overnight Moisturizer is a product with 34 ingredients: Acyl-Glutathione, Water, Butyrospermum Parkii (Shea) Butter, Myristyl Myristate, Niacinamide, C12-15 Alkyl Benzoate, Stearic Acid, Dimethicone, Sodium Acrylates Copolymer, Palmitoyl Glycine and 24 more.
Contains: AHA - Lactic Acid; Vitamins - Niacinamide; Antioxidant - Niacinamide, Lecithin, Macadamia Ternifolia (Macadamia) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract;
Organic score: 35% natural, 56% chemical. Vegan - No; Cruelty free - No; Reef safe - Yes;
Positive effects
Concerns
INCI - Full Breakdown
Water is a great solvent. It’s neutral and doesn’t provide any strong positive or negative effects. It just helps components to mix better and to transport active components.
Shea Butter is a great natural moisturizer everybody knows about. And it’s popular for a reason. It contains 5 essential fatty acids (palmitic, stearic, oleic, linoleic, and arachidonic), vitamins (A, D, E, F), and catechins, which are antioxidants. It moisturizes the skin and protects it from UV, cold, and other negative factors. It can be used on its own and will not harm your skin even in very high concentrations.

Myristyl Myristate is an emollient. It makes the product look consistent and feel smooth on the skin. The negative side is that it has a very high comedogenic rating. It may lead to clogged pores if you suffer from acne.
Niacinamide is a form of Vitamin B3 and it’s a superman in cosmetics. This ingredient is researched very well. It has a lot of positive reviews from scientists and experts. It's very important for healthy skin. The lack of this vitamin can cause dryness, itching, and sun sensitivity. The component removes small wrinkles and fine lines, heals wounds, and prevents the forming of cancer cells. It also makes the skin tone even by removing dark spots. It increases ceramide synthesis which increases the overall health of your skin. It fights acne and lowers pores.
Researches say that 4-5% of Niacinamide is the most effective concentration for skincare use.
C12-15 Alkyl Benzoate is mostly used as formulation component. It gives the product a soft and silky but non-greasy feeling. As for the skin benefits, it's an emollient – it makes the skin softer and more hydrated. It also helps to kill bacteria and increase the product’s shelf life.

Stearic Acid doesn’t belong to aggressive acids. It’s a fatty acid that can be found in Shea Butter, Cocoa Butter, and many natural butters and oils. The component is mostly used for formulation purposes. It makes the product spread and feel better. It’s one of the most important fatty acids in our skin cells.
Dimethicone is the most popular silicone. It makes the skin softer and forms a film adding smooth and silky feeling. This film not only improves how the skin feels but also works as a protective barrier. It also improves the visual appearance of your skin by filling small wrinkles. That's why some people think dimethicone removes wrinkles. Actually, it does not. It's just a visual effect.
One of the most important characteristics of this component is that it helps to spread other ingredients evenly on the surface to provide good coverage. It's very important because you want all your skin cells to receive an equal proportion of the components.
Dimethicone is considered as safe, but remember that it is rather difficult to wash off! This may lead to clogged pores and acne if you use it too often and don't wash off quite well.
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