ISDINNutratopic Crema FacialIngredients

Glycine is the building block of skin proteins. But you should know one important thing: the body can produce this component itself and it will not accept the ingredient you put on your skin for this purpose. It will not help to improve your own glycine level. As a cosmetic component, it can work only on the surface of your skin.

Carbomer is used for formulation purposes. It helps to control the viscosity and flow of a product. It’s considered safe but only if it’s well purified. Poorly purified carbomers may contain benzol which may lead to irritation.

Squalane is a more stable equivalent of Squalene. It is a very important component of our skin. It’s a major part of natural sebum that forms a protection barrier on the skin's surface. If the barrier isn’t strong enough, your skin will become more sensitive. Squalane helps to keep skin hydrated, protects it from the negative impact of the environment, lowers irritation, stimulates regeneration, and removes dryness. It is accepted by our skin very well and will not cause allergic reactions.

Xanthan Gum is used as a thickener or rheology modifier and emulsion stabilizer. It doesn’t provide any notable skin-related effects and is used mostly for formulation purposes. It makes the product’s texture smooth and even. It’s a naturally-derived thickener. Notable fact: it can also be found in the food you eat every day, so it is 100% safe.

Sodium Hydroxide is used mostly for formulation purposes. It helps to hold the pH level of a product. It also works as a chemical exfoliator that removes dead cells. Usually concentration of this component is low in skin care products and it’s used mostly for adjusting pH.

Ceramide NP is one of the most important ceramides found naturally in human skin. It plays a key role in maintaining a strong, healthy moisture barrier — the skin’s protective shield. When this barrier is damaged, skin becomes dry, irritated, and more sensitive. It helps restore that balance.

In skincare formulas, the component works by filling in the microscopic gaps between skin cells, much like mortar between bricks. This strengthens the outer layer of the skin, reduces moisture loss, and enhances overall resilience. Products containing Ceramide NP are especially beneficial for dry, sensitive, or compromised skin, including conditions like irritation from over-exfoliating or cold weather exposure.

Its biggest advantage is biocompatibility: Ceramide NP closely mimics the skin’s own natural ceramides, making it highly effective and well-tolerated. When combined with cholesterol and fatty acids, its performance is even better, helping to rebuild the lipid barrier more efficiently.

Overall, Ceramide NP is a gentle yet powerful ingredient that supports long-term skin health by reinforcing hydration, smoothing texture, and improving the skin’s ability to protect itself.

Citric Acid is one of the AHAs and it is a super useful component! It’s a great antioxidant. It acts as a soft peeling that removes dead cells and kills bacteria. It becomes even more effective if used with other cosmetic acids. Combined formulations are more active, but can irritate sensitive skin if used too often. The component can also whiten the skin and remove dark areas.

It can be an irritator due to its naturally lower pH level of 2.2. But manufacturers also use it as a pH adjuster so in most cases you will not have any issues.