CVS HealthRefining Retinol SerumIngredients

Polysorbate-60 is an emulsifier, foam stabilizer, and surfactant. It’s considered to be safe but if the product contains PEG ingredients, Polysorbate may produce 1,4-Dioxane which can be harmful to your health.

Polysorbate 20 doesn’t have any notable skin benefits but is used in cosmetics quite often. Manufacturers use it for formulation purposes. It improves the scent, texture, and feel of the product.

Caprylic/Capric Triglyceride is an emollient that also hydrates the skin without leaving a fatty film. When applied, the component feels smooth and light. In haircare products, it’s also used for hydrating purposes. It makes hair silky, lowers tangling, and makes hair smooth.

It’s safe for most people, except for people with allergic reactions to coconut or palm oil because these oils are usually used for producing the component.

Ceramide NP is one of the most important ceramides found naturally in human skin. It plays a key role in maintaining a strong, healthy moisture barrier — the skin’s protective shield. When this barrier is damaged, skin becomes dry, irritated, and more sensitive. It helps restore that balance.

In skincare formulas, the component works by filling in the microscopic gaps between skin cells, much like mortar between bricks. This strengthens the outer layer of the skin, reduces moisture loss, and enhances overall resilience. Products containing Ceramide NP are especially beneficial for dry, sensitive, or compromised skin, including conditions like irritation from over-exfoliating or cold weather exposure.

Its biggest advantage is biocompatibility: Ceramide NP closely mimics the skin’s own natural ceramides, making it highly effective and well-tolerated. When combined with cholesterol and fatty acids, its performance is even better, helping to rebuild the lipid barrier more efficiently.

Overall, Ceramide NP is a gentle yet powerful ingredient that supports long-term skin health by reinforcing hydration, smoothing texture, and improving the skin’s ability to protect itself.

Carbomer is used for formulation purposes. It helps to control the viscosity and flow of a product. It’s considered safe but only if it’s well purified. Poorly purified carbomers may contain benzol which may lead to irritation.

Glycerin is one of the most outstanding and helpful skincare components. It's used in many skincare products because it works and provides notable results. It's one of the best moisturizers. Molecules of Glycerin can absorb water and deliver it into deep layers of the skin making it hydrated.

Phenoxyethanol is one of the most popular preservatives. It kills bacteria and makes the product live longer. Manufacturers like this ingredient because it can dissolve in any liquid, even in oils.

Another purpose of this component is the fixation of aromas in perfumery. Phenoxyethanol is also used as a strong antiseptic and a good antibacterial agent. It is widely used in dermatological cosmetics alongside natural antiseptics such as chamomile, sage, and calendula.

Potassium Phosphate is an inorganic salt commonly used in cosmetics and skincare formulations. While it’s not a “hero ingredient” like niacinamide or ceramides, it plays important supporting roles that help a product stay stable, comfortable on the skin, and effective.

Potassium Phosphate (often listed as Dipotassium Phosphate or Monopotassium Phosphate depending on its form) is a buffering and chelating agent. In skincare chemistry, it helps regulate and maintain a product's pH balance — a crucial factor for both stability and skin compatibility. It helps to achieve PH balance by preventing the formula from becoming too acidic or too alkaline over time.

Main Functions:

• pH Buffering Agent - Its primary purpose is to stabilize pH. Many active ingredients — such as niacinamide, ceramides, or hyaluronic acid — perform best within a particular pH range. Potassium Phosphate ensures they stay effective throughout the product’s shelf life.
• Stabilizer for Emulsions - In creams and lotions, it helps maintain the stability of emulsions (the blend of water and oils), preventing unwanted separation.
• Enhances Product Comfort - A stable pH often means better skin tolerance. By keeping the formula balanced, Potassium Phosphate indirectly helps reduce the risk of stinging, redness, and irritation, especially in sensitive skin.
• Supports Ingredient Performance - Some actives can lose potency if the formula drifts out of range. Potassium Phosphate keeps the environment optimal, protecting their performance.

Xanthan Gum is used as a thickener or rheology modifier and emulsion stabilizer. It doesn’t provide any notable skin-related effects and is used mostly for formulation purposes. It makes the product’s texture smooth and even. It’s a naturally-derived thickener. Notable fact: it can also be found in the food you eat every day, so it is 100% safe.

Ethylhexylglycerin makes the skin softer, smoother and more hydrated. It acts deeply but without any heavy or sticky feeling. In haircare products, it works as a conditioner and scalp cleanser. It is safe but only in concentration below 8% in rinse-off products and below 2% in leave-on products. Can be an irritator in higher concentrations. In general, this component is great if you see it somewhere at the bottom of the list.

Citric Acid is one of the AHAs and it is a super useful component! It’s a great antioxidant. It acts as a soft peeling that removes dead cells and kills bacteria. It becomes even more effective if used with other cosmetic acids. Combined formulations are more active, but can irritate sensitive skin if used too often. The component can also whiten the skin and remove dark areas.

It can be an irritator due to its naturally lower pH level of 2.2. But manufacturers also use it as a pH adjuster so in most cases you will not have any issues.